博士，博士生导师，二级研究员
1986年毕业于西北农林科技大学。1989年获西北农林科技大学植物病理学理学硕士学位。2006年获中国科学院生态环境研究中心理学博士学位。2002年在澳大利亚Adelaide大学和南澳大利亚科学与发展研究院(SARDI)从事合作研究。在国内外学术刊物上发表论文60余篇，其中以第一作者或通讯作者在国际知名期刊上发表SCI论文50余篇，获授权国家发明专利14项。作为主要完成人，选育出高优503、科农9204、科农199、小偃597、科农213、科农1093等国审及省审小麦新品种9个，获2014年、2002年国家科技进步二等奖，2017年、2013年中华农业科技奖一等奖，2001年中国科学院科技进步一等奖。获2016年中国科学院朱李月华优秀教师奖，2018年益海嘉里优秀教师奖与“河北省直三八红旗手”及2021年“河北省直优秀共产党员”等荣誉。
小麦染色体工程材料的创制、抗病和重要农艺性状基因/QTL的发掘、精细定位与克隆及分子设计育种。
研究内容:
利用分子染色体工程、分子育种与常规技术相结合，发掘小麦近缘稀有种、农家品种、育成品种和国外引进材料中的重要基因/QTL及其优异等位变异；利用基因组学和新的测序手段开展相关基因的克隆与功能研究，解析作物高产、抗病和优质的分子遗传学基础，开发育种可用分子标记；结合全基因组分子标记选择技术和常规育种，创制和培育高产、多抗、优质专用的小麦种质资源和新品种。
1. 国家重点研发计划项目课题：小麦品质优异种质资源精准鉴定
2. 国家重点研发计划项目子课题：小麦抗白粉病优异种质资源精准鉴定
3. 国家自然科学基金面上项目：小麦广谱抗白粉病新基因的图位克隆、功能解析及标记辅助育种利用
4. 中科院战略性先导科技专项：冬小麦高产抗病品种的精准设计
发表主要论文 (#共同第一，* 通讯作者)
1. Han GH,Yan HW,Li LH*,An DG*. Advancing wheat breeding using rye: a key contribution to wheat breeding history. Trends in Biotechnology,2025,doi.org/10.1016/j.tibtech.2025.03.008.
2. Yan HW#,Han GH#,Gu TT,Shi ZP,Cao LJ,Wang J,Liu H,Wang CL,Zhuo SY,Li LH*, An DG*. Cytogenetic characterization of a novel wheat-rye 2R(2D) substitution line YT9 conferring powdery mildew resistance from the three-leaf stage and physical mapping of PmYT9. Theoretical and Applied Genetics,2025,138:167,doi.org/10.1007/s00122-025-04955-3.
3. Han GH#,Liu H#,Zhu SY#,Gu TT,Cao LJ,Yan HW,Jin YL,Wang J,Liu SY,Zhou YL,Shi ZP,He HG*,An DG*. Two functional CC-NBS-LRR proteins from rye chromosome 6RS confer differential age-related powdery mildew resistance to wheat. Plant Biotechnology Journal,2024,66-81.
4. Liu H#,Shi ZP#,Han GH,Zhang JP,Gu TT,Wang J,Yan HW,Xing LX,Li LH*, An DG*. A rare natural variation in TaFT-D2 underlies QTss.cas-3D associated with increased total spikelet number per spike in wheat. The Crop Journal,2024,12(6):1727-1734.
5. Shi ZP#,Han GH#,Gu TT#,Yan HW,Chang YJ,Zhou SY,Cao LJ,Xing LX,Liu YP,Li XF,Zhang YL*,An DG*. Multi-dimensional comprehensive evaluation reveals the characteristics of quality traits of wheat cultivars in the Huang-Huai wheat region of China. Journal of Integrative Agriculture,2024,doi:10.1016/j.jia.2024.12.029.
6. Xing LX#,Gu TT#,Shi FY,Jin YL,Fu XY,Han GH,Xu HX,Zhou YL,Liu W,He MQ*,An DG*. Characterization of a powdery mildew resistance gene in wheat breeding line Jingzi 102 using bulk segregant RNA sequencing. Plant Disease,2024,108: 3084-3091.
7. Han GH,Xing LX,Gu TT,Jin YL,Shi FY,Yan HW,Zhou SYShi ZP,Wang J,Zhou YL,Liu W,Zhang YL*,An DG*. Molecular identification of a Pm4 allele conferring powdery mildew resistance in durum wheat DR88. BMC Plant Biology,2024,24(1):1169.
8. Wang J,Han GH,Liu H,Yan HW,Jin YL,Cao LJ,Zhou YL,An DG*. Development of novel wheat‑rye 6RS small fragment translocation lines with powdery mildew resistance and physical mapping of the resistance gene PmW6RS. Theoretical and Applied Genetics,2023,136:179.
9. Han GH,Wang Jing,Yan HW, Gu TT,Cao LJ, Liu SY, Li XQ, Zhou YL, Fan JR, Shi ZP, Liu H, Li LH*, An DG*. Development and identification of two novel wheat-rye 6R derivative lines with adult-plant resistance to powdery mildew and high-yielding potential. The Crop Journal,2024,12(1):308-313.
10. Han GH#,Cao LJ#, Yan HW, Gu TT,Shi ZP, Li XQ, Li LH*, An DG*. Development and identification of a wheat-rye breeding line for harmonious improvement between powdery mildew resistance and high yield potential.Plant Disease,2023,107: 2453-2459.
11. Han GH,Wang Jing,Yan HW, Cao LJ, Liu SY, Li XQ, Zhou YL, Liu W,Gu TT, Shi ZP, Liu H, Li LH*, An DG*. Development and molecular cytogenetic identification of a new wheat-rye 6RL ditelosomic addition and 1R (1B) substitution line with powdery mildew resistance. Journal of Integrative Agriculture,2023,doi:10.1016/j.jia.2023.10.004.
12. Ma FF,Xu YF,Wang RF,Tong YP,Zhang AM,Liu DC*, An DG*. Identification of major QTLs for yield-related traits with improved genetic map in wheat. Frontiers in Plant Science,2023,14,doi:10.3389/fpls.2023.1138696.
13. Han GH#,Yan HW#,Gu TT,Cao LJ,Zhou YL,Liu W,Liu DC*,An DG*. Identification of a wheat powdery mildew dominant resistance gene in the Pm5 locus for high-throughput marker-assisted selection. Plant Disease,2023,107:450-456.
14. Xu YF#,Ma FF#,Zhang JP,Liu H,Li LH*,An DG*. Unraveling the genetic basis of grain number-related traits in a wheat-Agropyron cristatum introgressed line through high-resolution linkage mapping. BMC Plant Biology,2023,23:563,doi:10.1186/s12870-023-04547-7.
15. An DG*,Han GH,Wang J,Yan HW, Zhou YL, Cao LJ,Jin YL,Zhang XT. Cytological and genetic analyses of a wheat-rye 2RLditelosomicaddition line withadult plant resistance to powdery mildew. The Crop Journal,2022,10(3):911-916.
16. Han GH,Li HW,Cao LJ,Liu SY,Yan HW,Wang J,Zhou YL,An DG*. A novel wheat-rye 2R (2D) disomic substitution line pyramids two types of resistance to powdery mildew. Plant Disease,2022,106(9):2433-2440.
17. Han GH#,Yan HW#,Wang J,Cao LJ,Liu SY,Li XQ,Zhou YL,Fan JR,Li LH*,An DG*. Molecular cytogenetic identification of a new wheat-rye 6R addition line and physical localization of its powdery mildew resistance gene. Frontiers in Plant Science,2022,13:889494.
18. Jin YL#,Liu H#,Gu TT,Xing LX,Han GH,Ma PT,Li XQ,Zhou YL,Fan JR,Li LH*,An DG*. PM2b,a CC-NBS-LRR protein,interacts with TaWRKY76-D to regulate powdery mildew resistance in common wheat. Frontiers in Plant Science,2022,13:973065.
19. Jin YL#,Gu TT#,Li XQ,Liu H,Han GH,Shi ZP,Zhou YL,Fan JR,Wang J,Liu W,Zhao H*,An DG*. Characterization of a new splicing variant of powdery mildew resistance gene Pm4 in synthetic hexaploid wheat YAV249. Frontiers in Plant Science, 2022,13:1048252.
20. Liu H#,Shi ZP#,Ma FF,Xu YF,Han GH,Zhang JP,Liu DC*,An DG*. Identification and validation of plant height,spike length and spike compactness loci in common wheat. BMC Plant Biology,2022,22:568.
21. Liu H#,Han GH#,Gu TT#,Jin YL,Shi ZP,Xing LX,Yan HW,Wang J,Hao CY,Zhao MC*,An DG*. Identification of the major QTL QPm.cas-7D for adult plant resistance to wheat powdery mildew. Frontiers in Plant Science,2022,13:1042399.
22. Jin YL#,Shi FY#,Liu WH,Fu XY,Gu TT,Han GH,Shi ZP,Sheng Y,Xu HX,Li LH*,An DG*. Identification of resistant germplasm and detection of genes for resistance to powdery mildew and leaf rust from 2,978 wheat accessions. Plant Disease,2021,105(12):3900-3908.
23. Liu H#,Zhang XT#,Xu YF,Ma FF,Zhang JP,Cao YW,Li LH*,An DG*. Identification and validation of quantitative trait loci for kernel traits in common wheat. BMC Plant Biology,2020,20:529.
24. Han GH,Liu SY,Wang J,Jin YL,Zhou YL,Luo QL,Liu H,Zhao H*,An DG*. Identification of an elite wheat-rye T1RS·1BL translocation line conferring high resistance to powdery mildew and stripe rust. Plant Disease,2020,104:2940-2948.
25. Han GH#,Liu SY#,Jin YL,Jia MS,Ma PT,Liu H,Wang J,An DG*. Scale development and utilization of universal PCR-based and high-throughput KASP markers specific for chromosome arms of rye (Secale cereale L.). BMC Genomics,2020,21:206.
26. Ma PT#,Han GH#,Zheng Q,Liu SY,Han FP,Wang J,Luo QL,An DG*. Development of novel wheat-rye chromosome 4R translocations and assignment of their powdery mildew resistance. Plant Disease,2020,104(1):260-268.
27.An DG *,Ma PT,Zheng Q,Fu SL,Li LH,Han FP,Han GH,Wang J,Xu YF,Jin YL,Luo QL,Zhang XT. Development and molecular cytogenetic identification of a new wheat-rye 4R chromosome disomic addition line with resistances to powdery mildew,stripe rust and sharp eyespot. Theoretical and Applied Genetics,2019,132:257-272.
28. Qie YM#,Sheng Y#,Xu HX#,Jin YL,Ma FF,Li LH,Li XQ,An DG*. Identification of a new powdery mildew resistance gene pmDHT at or closely linked to the Pm5 locus in the Chinese wheat landrace Dahongtou. Plant Disease,2019,103(10):2645-2651.
29. Qie YM,Liu Y,Wang MN,Li X,See DR,An DG*,Chen XM*. Development,Validation,and Re-selection of Wheat Lines with Pyramided Genes Yr64 and Yr15 Linked on the Short Arm of Chromosome 1B for Resistance to Stripe Rust. Plant Disease,2019,103(1),51-58.
30. Ma PT,Xu HX,Xu YF,Song LP,Liang SS,Sheng Y,Han GH,Zhang XT,An DG*. Characterization of the powdery mildew resistance gene in wheat breeding line 10V-2 and its application in marker-assisted selection. Plant Disease,2018,102 (5):925-931.
31. Ma FF#,Xu YF#,Ma ZQ,Li LH,An DG*. Genome-wide association and validation of key loci for yield-related traits in wheat founder parent Xiaoyan 6. Molecular Breeding,2018,38:91.
32. Jin YL#,Xu HX#,Ma PT#,Fu XY,Song LP,Xu YF,Zhang XT,An DG*. Characterization of a new Pm2 allele associated with broad-spectrum powdery mildew resistance in wheat line Subtil. Scientific Reports,2018,8: 475.
33. Xu HX#,Cao YW#,Xu YF,Ma PT,Ma FF,Song LP,Li LH,An DG*. Marker-assisted development and evaluation of near-isogenic lines for broad-spectrum powdery mildew resistance gene Pm2b introgressed into different genetic backgrounds of wheat. Frontiers in Plant Science,2017,8:1322.
34. Xu YF,Li SS,Li LH,Ma FF,Fu XY,Shi ZL,Xu HX,Ma PT,An DG*. QTL mapping for yield and photosynthetic related traits under different water regimes in wheat. Molecular Breeding,2017,37:34.
35. Ma PT,Xu HX,Li LH,Han GH,Luo QL,Sun Y,Xu YF,Zhang XT,An DG*. Characterization of a segregation distortion locus with powdery mildew resistance in a wheat-Thinopyrum intermedium introgression line. Plant Disease,2016,100:1541-1547.
36. Ma PT,Xu HX,Li LH,Zhang HX,Han GH,Xu YF,Fu XY,Zhang XT,An DG*. Characterization of a new Pm2 allele conferring powdery mildew resistance in the wheat germplasm line FG-1. Frontiers in Plant Science, 2016,7:546.
37. Ma PT,Xu HX,Xu YF,Li LH*,Qie YM,Luo QL,Zhang XT,Li XQ,Zhou YL,An DG*. Molecular mapping of a new powdery mildew resistance gene Pm2b in Chinese breeding line KM2939. Theoretical and Applied Genetics,2015,128(4):613-622.
38. Xu HX,Yi YJ,Ma PT,Qie YM,Fu XY,Xu YF,Zhang XT,An DG*. Molecular tagging of a new broad-spectrum powdery mildew resistance allele Pm2c in Chinese wheat landrace Niaomai. Theoretical and Applied Genetics,2015,128(10):2077-2084.
39. Ma PT,Zhang HX,Xu HX,Xu YF,Cao YW,Zhang XT,An DG*. The gene PmYB confers broad-spectrum powdery mildew resistance in the multi-allelic Pm2 chromosome region of the Chinese wheat cultivar YingBo 700. Molecular Breeding,2015,35(5):124.
40. An DG*,Zheng Q,Luo QL,Ma PT,Zhang HX,Li LH,Han FP,Xu HX,Xu YF,Zhang XT,Zhou YL. Molecular cytogenetic identification of a new wheat-ry e 6R chromosome disomic addition line with powdery mildew resistance. PloS one,2015,10(8):e0134534.
41. Ma PT,Xu HX,Zhang HX,Li LH,Xu YF,Zhang XT,An DG*. The gene PmWFJ is a new member of the complex Pm2 locus conferring unique powdery mildew resistance in wheat breeding line Wanfengjian 34. Molecular Breeding,2015,210.
42. Xu YF#,Wang RF#,Tong YP,Zhao HT,Xie QE,Liu DC,Zhang AM,Li B,Xu HX,An DG*. Mapping QTLs for yield and nitrogen-related traits in wheat: influence of nitrogen and phosphorus fertilization on QTL expression. Theoretical and Applied Genetics,2014,127(1):59-72.
43. Xu HX,Zhang J,Zhang P,Qie YM,Niu YC,Li HJ,Ma PT,Xu YF,An DG*. Development and validation of molecular markers closely linked to the wheat stripe rust resistance gene YrC591 for marker-assisted selection. Euphytica,2014,198(3):317-323.
44. Ma PT,Xu HX,Luo QL,Qie YM,Zhou YL,Xu YF,Han HM,Li LH,An DG*. Inheritance and genetic mapping of a gene for seedling resistance to powdery mildew in wheat line X3986-2. Euphytica,2014,200(1):149-157.
45. An DG*, Zheng Qi,Zhou YL,Ma PT,Lv ZL,Li LH,Li B,Luo QL,Xu HX,Xu YF. Molecular cytogenetic characterization of a new wheat-rye 4R chromosome translocation line resistant to powdery mildew. Chromosome Research,2013,21:419-432.
46.Xu YF,Li SS,Li LH*,Zhang XT,Xu HX,An DG*. Mapping QTLs for salt tolerance with additive,epistatic and QTL × treatment interaction effects at seedling stage in wheat.Plant Breeding,2013,132,276-283.
47. Xu HX#,Yin DD#,Li LH,Wang QX,Li XQ,Yang XM,Liu WH,An DG*. Development and application of EST-based markers specific for chromosome arms of rye (Secale cereale L.). Cytogenet Genome Res,2012,136:220-228.
48. Huang J,Zhao ZH,Song FJ,Wang XM,Xu HX,Huang Y,An DG*,Li HJ*. Molecular detection of a gene effective against powdery mildew in the wheat cultivar Liangxing 66. Molecular Breeding,2012,30:1737-1745.
49. Xu YF,An DG*,Liu DC,Zhang AM,Xu HX and Li B. Molecular mapping of QTLs for grain zinc‚ iron and protein concentration of wheat across two environments. Field Crops Research,2012,138: 57-62.
50. Xu YF,An DG*,Liu DC,Zhang AM,Xu HX,Li B. Mapping QTLs with epistatic effects and QTL × treatment interactions for salt tolerance at seedling stage of wheat. Euphytica,2012,186(1):233-245.
51. Wang RF,An DG*,Hu CS,Li LH,Zhang YM,Jia YG,Tong YP*. Relationship between nitrogen uptake and use efficiency of winter wheat grown in the North China Plain. Crop and Pasture Science,2011,62: 504-514.
52. Xu YF,An DG*,Li HJ,Xu HX. Breeding wheat for enhanced micronutrients. Canadian Journal of Plant Science,2011,91 (2):1-7.
53. Wang CM,Zheng Q,Li LH,Niu YC,Wang HB,Li B,Zhang XT,Xu YF,An DG*. Molecular cytogenetic characterization of a new T2BL·1RS wheat-rye chromosome translocation line resistant to stripe rust and powdery mildew. Plant Disease,2009,93:124-129.
54. Wang CM,Li LH,Zhang XT,Gao Q,Wang RF,An DG*. Development and application of EST-STS markers specific to chromosome 1RS of Secale cereale. Cereal Research communications,2009,37:13-21.
55. An DG#,Su JY#,Liu QY,Zhu YG,Tong YP*,Li JM,Jing RL,Li B,Li ZS. Mapping QTLs for Nitrogen Uptake in relation to the early growth of wheat. Plant and Soil,2006,284:73-84.
56. An DG*,Li LH,Li JM,Li HJ,Zhu YG. Introgression of resistance to powdery mildew conferred by chromosome 2R by crossing wheat nullisomic 2D with rye. Journal of Integrative Plant Biology,2006,48: 838-847.
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中国科学院遗传与发育生物学研究所农业资源研究中心 京ICP备05002857号-1 地址：河北省石家庄市槐中路286号地理位置与乘车路线 邮编：050022 电话：0311-85814521传真：0311-85815093； Email:zhc@sjziam.ac.cn |
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